246 v. 740: think Variant vs. Alternate vs. Unrelated?
As we know, the 246 Marc field is used for the variant title of an item. Like the similar versions of the title appearing on the label, container, spine, etc. Or found in abbreviated form or make up full or part of the subtitle, and can be construed by someone as the actual title.
We use the 740 field to identify analytic titles within the item. So if you have a collective 245, the 740 will contain the titles of the individual parts that make up the collection (2nd indicator being 2). If we use the 740 to function as a related title, this will be a 2nd indicator 0) and you are compelled to have it traced.
So far I have gathered that the 246 is for the related work specifically in whole representation, and the 740 for any analytical work that is only part of the whole item or an unrelated title that is worth being traced.
I hope I have not oversimplified the distinction, but contributions and examples are encouraged for a better understanding.

